diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/include/interface.hpp b/ddtrace/internal/datadog/profiling/dd_wrapper/include/interface.hpp
index 34a985d1a16..adde7d01c37 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/include/interface.hpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/include/interface.hpp
@@ -21,6 +21,7 @@ extern "C"
     void ddup_config_profiler_version(std::string_view profiler_version);
     void ddup_config_url(std::string_view url);
     void ddup_config_max_nframes(int max_nframes);
+    void ddup_config_timeline(bool enable);
 
     void ddup_config_user_tag(std::string_view key, std::string_view val);
     void ddup_config_sample_type(unsigned int type);
@@ -56,6 +57,7 @@ extern "C"
                          std::string_view _filename,
                          uint64_t address,
                          int64_t line);
+    void ddup_push_monotonic_ns(Datadog::Sample* sample, int64_t monotonic_ns);
     void ddup_flush_sample(Datadog::Sample* sample);
     void ddup_drop_sample(Datadog::Sample* sample);
 
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/include/profile.hpp b/ddtrace/internal/datadog/profiling/dd_wrapper/include/profile.hpp
index 3af8251f5dc..d79c99f75f7 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/include/profile.hpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/include/profile.hpp
@@ -76,6 +76,6 @@ class Profile
     const ValueIndex& val();
 
     // collect
-    bool collect(const ddog_prof_Sample& sample);
+    bool collect(const ddog_prof_Sample& sample, int64_t endtime_ns);
 };
 } // namespace Datadog
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample.hpp b/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample.hpp
index 0a7b8750b6e..f28fdb07cf5 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample.hpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample.hpp
@@ -25,6 +25,12 @@ class Sample
     SampleType type_mask;
     std::string errmsg;
 
+    // Timeline support works by endowing each sample with a timestamp. Collection of this data this data is cheap, but
+    // due to the underlying pprof format, timeline support increases the sample cardinality. Rather than switching
+    // around the frontend code too much, we push enablement down to whether or not timestamps get added to samples (a
+    // 0 value suppresses the tag). However, Sample objects are short-lived, so we make the flag static.
+    static inline bool timeline_enabled = false;
+
     // Keeps temporary buffer of frames in the stack
     std::vector<ddog_prof_Location> locations;
     size_t dropped_frames = 0;
@@ -36,6 +42,9 @@ class Sample
     // Storage for values
     std::vector<int64_t> values = {};
 
+    // Additional metadata
+    int64_t endtime_ns = 0; // end of the event
+
   public:
     // Helpers
     bool push_label(ExportLabelKey key, std::string_view val);
@@ -62,6 +71,11 @@ class Sample
     bool push_trace_resource_container(std::string_view trace_resource_container);
     bool push_exceptioninfo(std::string_view exception_type, int64_t count);
     bool push_class_name(std::string_view class_name);
+    bool push_monotonic_ns(int64_t monotonic_ns);
+
+    // Interacts with static Sample state
+    bool is_timeline_enabled() const;
+    static void set_timeline(bool enabled);
 
     // Assumes frames are pushed in leaf-order
     void push_frame(std::string_view name,     // for ddog_prof_Function
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample_manager.hpp b/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample_manager.hpp
index ec6e388b96e..a5be316b8c6 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample_manager.hpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/include/sample_manager.hpp
@@ -24,6 +24,7 @@ class SampleManager
     // Configuration
     static void add_type(unsigned int type);
     static void set_max_nframes(unsigned int _max_nframes);
+    static void set_timeline(bool enable);
 
     // Sampling entrypoint (this could also be called `build_ptr()`)
     static Sample* start_sample();
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/src/interface.cpp b/ddtrace/internal/datadog/profiling/dd_wrapper/src/interface.cpp
index c0ccae883ee..ed158d7ca83 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/src/interface.cpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/src/interface.cpp
@@ -99,12 +99,19 @@ ddup_config_sample_type(unsigned int _type) // cppcheck-suppress unusedFunction
 {
     Datadog::SampleManager::add_type(_type);
 }
+
 void
 ddup_config_max_nframes(int max_nframes) // cppcheck-suppress unusedFunction
 {
     Datadog::SampleManager::set_max_nframes(max_nframes);
 }
 
+void
+ddup_config_timeline(bool enabled) // cppcheck-suppress unusedFunction
+{
+    Datadog::SampleManager::set_timeline(enabled);
+}
+
 bool
 ddup_is_initialized() // cppcheck-suppress unusedFunction
 {
@@ -247,6 +254,12 @@ ddup_push_frame(Datadog::Sample* sample, // cppcheck-suppress unusedFunction
     sample->push_frame(_name, _filename, address, line);
 }
 
+void
+ddup_push_monotonic_ns(Datadog::Sample* sample, int64_t monotonic_ns)
+{
+    sample->push_monotonic_ns(monotonic_ns);
+}
+
 void
 ddup_flush_sample(Datadog::Sample* sample) // cppcheck-suppress unusedFunction
 {
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/src/profile.cpp b/ddtrace/internal/datadog/profiling/dd_wrapper/src/profile.cpp
index 086e90ee495..6f986f4896b 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/src/profile.cpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/src/profile.cpp
@@ -184,11 +184,10 @@ Datadog::Profile::val()
 }
 
 bool
-Datadog::Profile::collect(const ddog_prof_Sample& sample)
+Datadog::Profile::collect(const ddog_prof_Sample& sample, int64_t endtime_ns)
 {
-    // TODO this should propagate some kind of timestamp for timeline support
     const std::lock_guard<std::mutex> lock(profile_mtx);
-    auto res = ddog_prof_Profile_add(&cur_profile, sample, 0);
+    auto res = ddog_prof_Profile_add(&cur_profile, sample, endtime_ns);
     if (!res.ok) {          // NOLINT (cppcoreguidelines-pro-type-union-access)
         auto err = res.err; // NOLINT (cppcoreguidelines-pro-type-union-access)
         const std::string errmsg = err_to_msg(&err, "Error adding sample to profile");
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample.cpp b/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample.cpp
index d2a28562505..eb7cacff295 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample.cpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample.cpp
@@ -1,5 +1,6 @@
 #include "sample.hpp"
 
+#include <chrono>
 #include <thread>
 
 Datadog::Sample::Sample(SampleType _type_mask, unsigned int _max_nframes)
@@ -117,7 +118,7 @@ Datadog::Sample::flush_sample()
         .labels = { labels.data(), labels.size() },
     };
 
-    const bool ret = profile_state.collect(sample);
+    const bool ret = profile_state.collect(sample, endtime_ns);
     clear_buffers();
     return ret;
 }
@@ -316,6 +317,47 @@ Datadog::Sample::push_class_name(std::string_view class_name)
     return true;
 }
 
+bool
+Datadog::Sample::push_monotonic_ns(int64_t _monotonic_ns)
+{
+    // Monotonic times have their epoch at the system start, so they need an
+    // adjustment to the standard epoch
+    // Just set a static for now and use a lambda to compute the offset once
+    const static auto offset = []() {
+        // Get the current epoch time
+        using namespace std::chrono;
+        auto epoch_ns = duration_cast<nanoseconds>(system_clock::now().time_since_epoch()).count();
+
+        // Get the current monotonic time.  Use clock_gettime directly because the standard underspecifies
+        // which clock is actually used in std::chrono
+        timespec ts;
+        clock_gettime(CLOCK_MONOTONIC, &ts);
+        auto monotonic_ns = static_cast<int64_t>(ts.tv_sec) * 1'000'000'000LL + ts.tv_nsec;
+
+        // Compute the difference.  We're after 1970, so epoch_ns will be larger
+        return epoch_ns - monotonic_ns;
+    }();
+
+    // If timeline is not enabled, then this is a no-op
+    if (is_timeline_enabled()) {
+        endtime_ns = _monotonic_ns + offset;
+    }
+
+    return true;
+}
+
+void
+Datadog::Sample::set_timeline(bool enabled)
+{
+    timeline_enabled = enabled;
+}
+
+bool
+Datadog::Sample::is_timeline_enabled() const
+{
+    return timeline_enabled;
+}
+
 ddog_prof_Profile&
 Datadog::Sample::profile_borrow()
 {
diff --git a/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample_manager.cpp b/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample_manager.cpp
index 72137b9a5d0..d4a864052e5 100644
--- a/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample_manager.cpp
+++ b/ddtrace/internal/datadog/profiling/dd_wrapper/src/sample_manager.cpp
@@ -21,6 +21,12 @@ Datadog::SampleManager::set_max_nframes(unsigned int _max_nframes)
     }
 }
 
+void
+Datadog::SampleManager::set_timeline(bool enable)
+{
+    Datadog::Sample::set_timeline(enable);
+}
+
 Datadog::Sample*
 Datadog::SampleManager::start_sample()
 {
diff --git a/ddtrace/internal/datadog/profiling/ddup/_ddup.pyi b/ddtrace/internal/datadog/profiling/ddup/_ddup.pyi
index deb1e23ffed..29749138a98 100644
--- a/ddtrace/internal/datadog/profiling/ddup/_ddup.pyi
+++ b/ddtrace/internal/datadog/profiling/ddup/_ddup.pyi
@@ -12,6 +12,7 @@ def init(
     tags: Optional[Dict[Union[str, bytes], Union[str, bytes]]],
     max_nframes: Optional[int],
     url: Optional[str],
+    timeline_enabled: Optional[bool],
 ) -> None: ...
 def upload() -> None: ...
 
@@ -30,4 +31,5 @@ class SampleHandle:
     def push_exceptioninfo(self, exc_type: Union[None, bytes, str, type], count: int) -> None: ...
     def push_class_name(self, class_name: StringType) -> None: ...
     def push_span(self, span: Optional[Span], endpoint_collection_enabled: bool) -> None: ...
+    def push_monotonic_ns(self, monotonic_ns: int) -> None: ...
     def flush_sample(self) -> None: ...
diff --git a/ddtrace/internal/datadog/profiling/ddup/_ddup.pyx b/ddtrace/internal/datadog/profiling/ddup/_ddup.pyx
index d76a5aecff7..51c6da81dbd 100644
--- a/ddtrace/internal/datadog/profiling/ddup/_ddup.pyx
+++ b/ddtrace/internal/datadog/profiling/ddup/_ddup.pyx
@@ -40,6 +40,7 @@ cdef extern from "interface.hpp":
     void ddup_config_profiler_version(string_view profiler_version)
     void ddup_config_url(string_view url)
     void ddup_config_max_nframes(int max_nframes)
+    void ddup_config_timeline(bint enable)
 
     void ddup_config_user_tag(string_view key, string_view val)
     void ddup_config_sample_type(unsigned int type)
@@ -64,6 +65,7 @@ cdef extern from "interface.hpp":
     void ddup_push_exceptioninfo(Sample *sample, string_view exception_type, int64_t count)
     void ddup_push_class_name(Sample *sample, string_view class_name)
     void ddup_push_frame(Sample *sample, string_view _name, string_view _filename, uint64_t address, int64_t line)
+    void ddup_push_monotonic_ns(Sample *sample, int64_t monotonic_ns)
     void ddup_flush_sample(Sample *sample)
     void ddup_drop_sample(Sample *sample)
     void ddup_set_runtime_id(string_view _id)
@@ -130,7 +132,8 @@ def init(
         version: StringType = None,
         tags: Optional[Dict[Union[str, bytes], Union[str, bytes]]] = None,
         max_nframes: Optional[int] = None,
-        url: StringType = None) -> None:
+        url: StringType = None,
+        timeline_enabled: Optional[bool] = None) -> None:
 
     # Try to provide a ddtrace-specific default service if one is not given
     service = service or DEFAULT_SERVICE_NAME
@@ -156,6 +159,8 @@ def init(
         for key, val in tags.items():
             if key and val:
                 call_ddup_config_user_tag(ensure_binary_or_empty(key), ensure_binary_or_empty(val))
+    if timeline_enabled is True:
+        ddup_config_timeline(True)
     ddup_init()
 
 
@@ -234,7 +239,6 @@ cdef class SampleHandle:
     def push_task_id(self, task_id: Optional[int]) -> None:
         if self.ptr is not NULL:
             if task_id is not None:
-                ddup_push_task_id(self.ptr, task_id)
                 ddup_push_task_id(self.ptr, clamp_to_int64_unsigned(task_id))
 
     def push_task_name(self, task_name: StringType) -> None:
@@ -282,6 +286,10 @@ cdef class SampleHandle:
                     string_view(<const char*>root_service_bytes, len(root_service_bytes))
             )
 
+    def push_monotonic_ns(self, monotonic_ns: int) -> None:
+        if self.ptr is not NULL:
+            ddup_push_monotonic_ns(self.ptr, <int64_t>monotonic_ns)
+
     def flush_sample(self) -> None:
         # Flushing the sample consumes it.  The user will no longer be able to use
         # this handle after flushing it.
diff --git a/ddtrace/internal/datadog/profiling/stack_v2/src/stack_renderer.cpp b/ddtrace/internal/datadog/profiling/stack_v2/src/stack_renderer.cpp
index 6f158aeeac8..dfda9e7e7ac 100644
--- a/ddtrace/internal/datadog/profiling/stack_v2/src/stack_renderer.cpp
+++ b/ddtrace/internal/datadog/profiling/stack_v2/src/stack_renderer.cpp
@@ -29,9 +29,18 @@ StackRenderer::render_thread_begin(PyThreadState* tstate,
         return;
     }
 
-    // #warning stack_v2 should use a C++ interface instead of re-converting intermediates
+    // Get the current time in ns in a way compatible with python's time.monotonic_ns(), which is backed by
+    // clock_gettime(CLOCK_MONOTONIC) on linux and mach_absolute_time() on macOS.
+    // This is not the same as std::chrono::steady_clock, which is backed by clock_gettime(CLOCK_MONOTONIC_RAW)
+    // (although this is underspecified in the standard)
+    timespec ts;
+    if (clock_gettime(CLOCK_MONOTONIC, &ts) == 0) {
+        auto now_ns = static_cast<int64_t>(ts.tv_sec) * 1'000'000'000LL + static_cast<int64_t>(ts.tv_nsec);
+        ddup_push_monotonic_ns(sample, now_ns);
+    }
+
     ddup_push_threadinfo(sample, static_cast<int64_t>(thread_id), static_cast<int64_t>(native_id), name);
-    ddup_push_walltime(sample, 1000 * wall_time_us, 1);
+    ddup_push_walltime(sample, 1000LL * wall_time_us, 1);
 }
 
 void
diff --git a/ddtrace/profiling/collector/_lock.py b/ddtrace/profiling/collector/_lock.py
index 35a673d52c5..3c6e32545fb 100644
--- a/ddtrace/profiling/collector/_lock.py
+++ b/ddtrace/profiling/collector/_lock.py
@@ -11,6 +11,7 @@
 from ddtrace._trace.tracer import Tracer
 from ddtrace.internal import compat
 from ddtrace.internal.datadog.profiling import ddup
+from ddtrace.internal.logger import get_logger
 from ddtrace.profiling import _threading
 from ddtrace.profiling import collector
 from ddtrace.profiling import event
@@ -21,6 +22,9 @@
 from ddtrace.vendor import wrapt
 
 
+LOG = get_logger(__name__)
+
+
 @event.event_class
 class LockEventBase(event.StackBasedEvent):
     """Base Lock event."""
@@ -118,6 +122,7 @@ def acquire(self, *args, **kwargs):
                     thread_native_id = _threading.get_thread_native_id(thread_id)
 
                     handle = ddup.SampleHandle()
+                    handle.push_monotonic_ns(end)
                     handle.push_lock_name(self._self_name)
                     handle.push_acquire(end - start, 1)  # AFAICT, capture_pct does not adjust anything here
                     handle.push_threadinfo(thread_id, thread_native_id, thread_name)
@@ -146,7 +151,8 @@ def acquire(self, *args, **kwargs):
                         event.set_trace_info(self._self_tracer.current_span(), self._self_endpoint_collection_enabled)
 
                     self._self_recorder.push_event(event)
-            except Exception:
+            except Exception as e:
+                LOG.warning("Error recording lock acquire event: %s", e)
                 pass  # nosec
 
     def release(self, *args, **kwargs):
@@ -172,6 +178,7 @@ def release(self, *args, **kwargs):
                             thread_native_id = _threading.get_thread_native_id(thread_id)
 
                             handle = ddup.SampleHandle()
+                            handle.push_monotonic_ns(end)
                             handle.push_lock_name(self._self_name)
                             handle.push_release(
                                 end - self._self_acquired_at, 1
@@ -208,7 +215,8 @@ def release(self, *args, **kwargs):
                             self._self_recorder.push_event(event)
                     finally:
                         del self._self_acquired_at
-            except Exception:
+            except Exception as e:
+                LOG.warning("Error recording lock release event: %s", e)
                 pass  # nosec
 
     acquire_lock = acquire
diff --git a/ddtrace/profiling/collector/memalloc.py b/ddtrace/profiling/collector/memalloc.py
index 06dd16463c0..9de3cb73136 100644
--- a/ddtrace/profiling/collector/memalloc.py
+++ b/ddtrace/profiling/collector/memalloc.py
@@ -13,6 +13,7 @@
 except ImportError:
     _memalloc = None  # type: ignore[assignment]
 
+from ddtrace.internal import compat
 from ddtrace.internal.datadog.profiling import ddup
 from ddtrace.profiling import _threading
 from ddtrace.profiling import collector
@@ -167,6 +168,7 @@ def collect(self):
                 if thread_id in thread_id_ignore_set:
                     continue
                 handle = ddup.SampleHandle()
+                handle.push_monotonic_ns(compat.monotonic_ns())
                 handle.push_alloc(int((ceil(size) * alloc_count) / count), count)  # Roundup to help float precision
                 handle.push_threadinfo(
                     thread_id, _threading.get_thread_native_id(thread_id), _threading.get_thread_name(thread_id)
diff --git a/ddtrace/profiling/collector/stack.pyx b/ddtrace/profiling/collector/stack.pyx
index 3ba4e8af103..6164f477191 100644
--- a/ddtrace/profiling/collector/stack.pyx
+++ b/ddtrace/profiling/collector/stack.pyx
@@ -290,7 +290,7 @@ cdef collect_threads(thread_id_ignore_list, thread_time, thread_span_links) with
     )
 
 
-cdef stack_collect(ignore_profiler, thread_time, max_nframes, interval, wall_time, thread_span_links, collect_endpoint):
+cdef stack_collect(ignore_profiler, thread_time, max_nframes, interval, wall_time, thread_span_links, collect_endpoint, now_ns = 0):
     # Do not use `threading.enumerate` to not mess with locking (gevent!)
     # Also collect the native threads, that are not registered with the built-in
     # threading module, to keep backward compatibility with the previous
@@ -331,6 +331,7 @@ cdef stack_collect(ignore_profiler, thread_time, max_nframes, interval, wall_tim
             if nframes:
                 if use_libdd:
                     handle = ddup.SampleHandle()
+                    handle.push_monotonic_ns(now_ns)
                     handle.push_walltime(wall_time, 1)
                     handle.push_threadinfo(thread_id, thread_native_id, thread_name)
                     handle.push_task_id(task_id)
@@ -358,6 +359,7 @@ cdef stack_collect(ignore_profiler, thread_time, max_nframes, interval, wall_tim
         if nframes:
             if use_libdd:
                 handle = ddup.SampleHandle()
+                handle.push_monotonic_ns(now_ns)
                 handle.push_cputime( cpu_time, 1)
                 handle.push_walltime( wall_time, 1)
                 handle.push_threadinfo(thread_id, thread_native_id, thread_name)
@@ -390,6 +392,7 @@ cdef stack_collect(ignore_profiler, thread_time, max_nframes, interval, wall_tim
             if nframes:
                 if use_libdd:
                     handle = ddup.SampleHandle()
+                    handle.push_monotonic_ns(now_ns)
                     handle.push_threadinfo(thread_id, thread_native_id, thread_name)
                     handle.push_exceptioninfo(exc_type, 1)
                     handle.push_class_name(frames[0].class_name)
@@ -541,6 +544,7 @@ class StackCollector(collector.PeriodicCollector):
                 wall_time,
                 self._thread_span_links,
                 self.endpoint_collection_enabled,
+                now_ns=now,
             )
 
         used_wall_time_ns = compat.monotonic_ns() - now
diff --git a/ddtrace/profiling/profiler.py b/ddtrace/profiling/profiler.py
index 4f5a893ba50..acd16b68469 100644
--- a/ddtrace/profiling/profiler.py
+++ b/ddtrace/profiling/profiler.py
@@ -217,6 +217,7 @@ def _build_default_exporters(self):
                     tags=self.tags,  # type: ignore
                     max_nframes=config.max_frames,
                     url=endpoint,
+                    timeline_enabled=config.timeline_enabled,
                 )
                 return []
             except Exception as e:
diff --git a/ddtrace/settings/profiling.py b/ddtrace/settings/profiling.py
index 71ba2dac9cc..74f02d07f57 100644
--- a/ddtrace/settings/profiling.py
+++ b/ddtrace/settings/profiling.py
@@ -170,6 +170,15 @@ class ProfilingConfig(En):
         help="The timeout in seconds before dropping events if the HTTP API does not reply",
     )
 
+    timeline_enabled = En.v(
+        bool,
+        "timeline_enabled",
+        default=False,
+        help_type="Boolean",
+        help="Whether to add timestamp information to captured samples.  Adds a small amount of "
+        "overhead to the profiler, but enables the use of the Timeline view in the UI.",
+    )
+
     tags = En.v(
         dict,
         "tags",