diff --git a/sdk/monitor/azure-monitor-opentelemetry/CHANGELOG.md b/sdk/monitor/azure-monitor-opentelemetry/CHANGELOG.md
index 3edb63736a26..5f73d8ff988c 100644
--- a/sdk/monitor/azure-monitor-opentelemetry/CHANGELOG.md
+++ b/sdk/monitor/azure-monitor-opentelemetry/CHANGELOG.md
@@ -8,6 +8,8 @@
   ([#43262](https://github.com/Azure/azure-sdk-for-python/pull/43262))
 - Adding more diagnostic log message IDs
   ([#43183](https://github.com/Azure/azure-sdk-for-python/pull/43183))
+- Enable Azure AI Project instrumentation
+    ([#43869](https://github.com/Azure/azure-sdk-for-python/pull/43869))
 
 ### Breaking Changes
 
diff --git a/sdk/monitor/azure-monitor-opentelemetry/azure/monitor/opentelemetry/_configure.py b/sdk/monitor/azure-monitor-opentelemetry/azure/monitor/opentelemetry/_configure.py
index 12c71174cb22..e5214b3264b4 100644
--- a/sdk/monitor/azure-monitor-opentelemetry/azure/monitor/opentelemetry/_configure.py
+++ b/sdk/monitor/azure-monitor-opentelemetry/azure/monitor/opentelemetry/_configure.py
@@ -357,6 +357,7 @@ def _setup_additional_azure_sdk_instrumentations(configurations: Dict[str, Confi
     instrumentors = [
         ("azure.ai.inference.tracing", "AIInferenceInstrumentor"),
         ("azure.ai.agents.telemetry", "AIAgentsInstrumentor"),
+        ("azure.ai.projects.telemetry", "AIProjectInstrumentor"),
     ]
 
     for module_path, class_name in instrumentors: