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Intro & figure layout #3

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jkim0731 opened this issue Feb 2, 2024 · 0 comments
Open

Intro & figure layout #3

jkim0731 opened this issue Feb 2, 2024 · 0 comments

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@jkim0731
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jkim0731 commented Feb 2, 2024

1st draft of intro & figure layout:
https://alleninstitute.sharepoint.com/:w:/s/LearningmFISH/EZ7hqkqpQRtCpTAq4tiTcUgBqc_zvTUjAkvwspy5xKdWcQ?e=kmKNmf

Analysis goals:

  1. Familiarization index (Figure 2)
    • Image responses to familiar images across training + novel image response
    • The same with omission responses
  2. Functional clustering (Figure 3)
    • Clustering using coding score (with improved encoding model)
    • Clustering using traces
  3. Functional interaction (Figure 4)
    • Target specific known potential disinhibitory circuit (L2/3 VIP-SST, L4 SST-PV)
    • Noise correlation (with better encoding model to subtract)

Stand-up meetings (Jinho & Matt):

  • Quick updates and issue sharing
  • Mon/Thu 10.30 am
  • Optional: Arielle & Marina

Data:

  1. First test with GCaMP pilot data
  2. Then use most recent GAD2 or VGAT-Cre data
  3. Once having co-registered data, focus on them.
    • Power analysis (for number of cells and mice)
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