diff --git a/app/errors/twilio_errors.rb b/app/errors/twilio_errors.rb
index e2f3d37f763..731552437ef 100644
--- a/app/errors/twilio_errors.rb
+++ b/app/errors/twilio_errors.rb
@@ -4,6 +4,7 @@ module TwilioErrors
     21_211 => I18n.t('errors.messages.invalid_phone_number'),
     21_215 => I18n.t('errors.messages.invalid_calling_area'),
     21_614 => I18n.t('errors.messages.invalid_sms_number'),
+    4_815_162_342 => I18n.t('errors.messages.twilio_timeout'),
   }.freeze
 
   VERIFY_ERRORS = {
diff --git a/app/services/twilio_service.rb b/app/services/twilio_service.rb
index fb866c21b61..1e72e04d662 100644
--- a/app/services/twilio_service.rb
+++ b/app/services/twilio_service.rb
@@ -7,6 +7,7 @@ class Utils
     end
 
     def initialize
+      @http_client = Twilio::HTTP::Client.new(timeout: Figaro.env.twilio_timeout.to_i)
       @client = if FeatureManagement.telephony_disabled?
                   NullTwilioClient.new
                 else
@@ -41,13 +42,10 @@ def from_number
 
     private
 
-    attr_reader :client
+    attr_reader :client, :http_client
 
     def twilio_client
-      telephony_service.new(
-        TWILIO_SID,
-        TWILIO_AUTH_TOKEN
-      )
+      telephony_service.new(TWILIO_SID, TWILIO_AUTH_TOKEN, nil, nil, @http_client)
     end
 
     def random_phone_number
@@ -59,6 +57,8 @@ def sanitize_errors
     rescue Twilio::REST::RestError => error
       sanitize_phone_number(error.message)
       raise
+    rescue Faraday::TimeoutError
+      raise Twilio::REST::RestError.new('timeout', TwilioTimeoutResponse.new)
     end
 
     DIGITS_TO_PRESERVE = 5
@@ -72,5 +72,15 @@ def sanitize_phone_number(str)
         end
       end
     end
+
+    class TwilioTimeoutResponse
+      def status_code
+        4_815_162_342
+      end
+
+      def body
+        {}
+      end
+    end
   end
 end
diff --git a/config/application.yml.example b/config/application.yml.example
index 77a0f3c89d9..cdfa2f6fb81 100644
--- a/config/application.yml.example
+++ b/config/application.yml.example
@@ -67,6 +67,7 @@ use_dashboard_service_providers: 'false'
 dashboard_url: 'https://dashboard.demo.login.gov'
 valid_authn_contexts: '["http://idmanagement.gov/ns/assurance/loa/1", "http://idmanagement.gov/ns/assurance/loa/3"]'
 
+twilio_timeout: '5'
 usps_upload_sftp_timeout: '5'
 
 development:
diff --git a/config/initializers/figaro.rb b/config/initializers/figaro.rb
index 268bd73444f..06de0362e43 100644
--- a/config/initializers/figaro.rb
+++ b/config/initializers/figaro.rb
@@ -49,6 +49,7 @@
   'twilio_auth_token',
   'twilio_record_voice',
   'twilio_messaging_service_sid',
+  'twilio_timeout',
   'use_kms',
   'valid_authn_contexts'
 )
diff --git a/config/locales/errors/en.yml b/config/locales/errors/en.yml
index 423bacf7616..45509a05bc3 100644
--- a/config/locales/errors/en.yml
+++ b/config/locales/errors/en.yml
@@ -44,6 +44,7 @@ en:
       phone_unsupported: Sorry, we are unable to send SMS at this time. Please try
         the phone call option below, or use your personal key.
       twilio_inbound_sms_invalid: The inbound Twilio SMS message failed validation.
+      twilio_timeout: The server took too long to respond. Please try again.
       unauthorized_authn_context: Unauthorized authentication context
       unauthorized_nameid_format: Unauthorized nameID format
       unauthorized_service_provider: Unauthorized Service Provider
diff --git a/config/locales/errors/es.yml b/config/locales/errors/es.yml
index ec1c8027781..62205656ae9 100644
--- a/config/locales/errors/es.yml
+++ b/config/locales/errors/es.yml
@@ -40,6 +40,7 @@ es:
       phone_unsupported: Lo sentimos, no podemos enviar SMS en este momento. Pruebe
         la opción de llamada telefónica a continuación o use su clave personal.
       twilio_inbound_sms_invalid: El mensaje de Twilio SMS de entrada falló la validación.
+      twilio_timeout: NOT TRANSLATED YET
       unauthorized_authn_context: Contexto de autenticación no autorizado
       unauthorized_nameid_format: NOT TRANSLATED YET
       unauthorized_service_provider: Proveedor de servicio no autorizado
diff --git a/config/locales/errors/fr.yml b/config/locales/errors/fr.yml
index c082243df38..bab66df7b11 100644
--- a/config/locales/errors/fr.yml
+++ b/config/locales/errors/fr.yml
@@ -42,6 +42,7 @@ fr:
         le moment. S'il vous plaît essayez l'option d'appel téléphonique ci-dessous,
         ou utilisez votre clé personnelle.
       twilio_inbound_sms_invalid: Le message SMS Twilio entrant a échoué à la validation.
+      twilio_timeout: NOT TRANSLATED YET
       unauthorized_authn_context: Contexte d'authentification non autorisé
       unauthorized_nameid_format: NOT TRANSLATED YET
       unauthorized_service_provider: Fournisseur de service non autorisé
diff --git a/spec/services/twilio_service_spec.rb b/spec/services/twilio_service_spec.rb
index 36a577875c0..d8cc7409821 100644
--- a/spec/services/twilio_service_spec.rb
+++ b/spec/services/twilio_service_spec.rb
@@ -40,10 +40,15 @@
       TwilioService::Utils.telephony_service = Twilio::REST::Client
     end
 
-    it 'uses a real Twilio client' do
+    it 'uses a real Twilio client with timeout' do
+      allow(Figaro.env).to receive(:twilio_timeout).and_return('1')
       client = instance_double(Twilio::REST::Client)
+      twilio_http_client = instance_double(Twilio::HTTP::Client)
+      expect(Twilio::HTTP::Client).to receive(:new).with(timeout: 1).and_return(twilio_http_client)
       expect(Twilio::REST::Client).
-        to receive(:new).with(/sid(1|2)/, /token(1|2)/).and_return(client)
+        to receive(:new).
+        with(/sid(1|2)/, /token(1|2)/, nil, nil, twilio_http_client).
+        and_return(client)
       http_client = Struct.new(:adapter)
       expect(client).to receive(:http_client).and_return(http_client)
       expect(http_client).to receive(:adapter=).with(:typhoeus)
@@ -95,6 +100,21 @@
       expect { service.place_call(to: '+123456789012', url: 'https://twimlet.com') }.
         to raise_error(Twilio::REST::RestError, sanitized_message)
     end
+
+    it 'rescues timeout errors and raises a custom Twilio error' do
+      TwilioService::Utils.telephony_service = FakeVoiceCall
+      error_code = 4_815_162_342
+      status_code = 4_815_162_342
+
+      message = "[HTTP #{status_code}] #{error_code} : timeout\n\n"
+      service = TwilioService::Utils.new
+
+      expect(service.send(:client).calls).to receive(:create).
+        and_raise(Faraday::TimeoutError)
+
+      expect { service.place_call(to: '+123456789012', url: 'https://twimlet.com') }.
+        to raise_error(Twilio::REST::RestError, message)
+    end
   end
 
   describe '#send_sms' do
@@ -137,5 +157,20 @@
       expect { service.send_sms(to: '+1 (888) 555-5555', body: 'test') }.
         to raise_error(Twilio::REST::RestError, sanitized_message)
     end
+
+    it 'rescues timeout errors and raises a custom Twilio error' do
+      TwilioService::Utils.telephony_service = FakeSms
+      error_code = 4_815_162_342
+      status_code = 4_815_162_342
+
+      message = "[HTTP #{status_code}] #{error_code} : timeout\n\n"
+      service = TwilioService::Utils.new
+
+      expect(service.send(:client).messages).to receive(:create).
+        and_raise(Faraday::TimeoutError)
+
+      expect { service.send_sms(to: '+123456789012', body: 'test') }.
+        to raise_error(Twilio::REST::RestError, message)
+    end
   end
 end
diff --git a/spec/support/fake_sms.rb b/spec/support/fake_sms.rb
index 1e4e3c62862..f884cf2e64d 100644
--- a/spec/support/fake_sms.rb
+++ b/spec/support/fake_sms.rb
@@ -5,7 +5,7 @@ class FakeSms
   cattr_accessor :messages
   self.messages = []
 
-  def initialize(_account_sid, _auth_token); end
+  def initialize(_username, _password, _account_sid, _region, _http_client); end
 
   def messages
     self
diff --git a/spec/support/fake_voice_call.rb b/spec/support/fake_voice_call.rb
index 4a5512a3e0b..f5afeb89093 100644
--- a/spec/support/fake_voice_call.rb
+++ b/spec/support/fake_voice_call.rb
@@ -4,7 +4,7 @@ class FakeVoiceCall
   cattr_accessor :calls
   self.calls = []
 
-  def initialize(_account_sid, _auth_token); end
+  def initialize(_username, _password, _account_sid, _region, _http_client); end
 
   def calls
     self